Advanced BioMatrix is a leader in the life science of three dimensional (3D) applications for tissue culture, cell assay, and cell proliferation. Company’s products are recognized as the standard for purity, functionality, and consistency.
Advanced BioMatrix manufacturers and distributes high quality collagen including PureCol® for cell culture, gels, coatings and other research uses.
Advanced BioMatrix product portfolio provides an in vivo-like 3D matrix environment for attachment, growth, and assay of a vast number of cell types/lines.
Why 3D Matters:
3D gels allow for the study of the effects of the mechanical properties of the ECM, such as density and rigidity, on cell development, migration, and morphology. Unlike 2D systems, 3D environments allow cell extensions to simultaneously interact with integrins on all cell surfaces, resulting in the activation of specific signaling pathways. Gel stiffness or rigidity also affects cell migration differently in 3D versus 2D environments. Furthermore, integrin-independent mechanical interactions resulting from the entanglement of matrix fibrils with cell extensions are possible in 3D systems, but not in 2D systems where the cells are attached to a flat surface.
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